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KMID : 0359019960160010082
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Korean Journal of Gastrointestinal Endoscopy
1996 Volume.16 No. 1 p.82 ~ p.88
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A Case of Gastric Ulcer Associated with Mucormycosis
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권건호
이돈행/송시영/김세규/강진경/박인서/이상엽/박찬일
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Abstract
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Mucormycosis is an uncommon, frequently fatal, opportunistic fungal infection. Rhinocerebral and pulmonary involvement are the most common forms and usually occur in immunecompromised patients. Gastrointestinal involvement is extremely rare, the
stomach
being the most frequently involved site among them. When gastric mucormycosis presents as an invasive fungal infection the prognosis is extremely poor. Alternatively when the fungus may colonize the gastric mucosa without invasion of the blood
vessels,
the prognosis is good. Early diagnosis and timely institution of aggressive treatment is essential for the patients with mucormycosis.
We report a 72-year-old man of gastric mucormycosis confirmed by histologic examination of endoscopic biopsy specimen. The patient was admitted to intensive care unit under the diagnosis of adult respiratory distress syndrome and sepsis. He has
been
suffered from 5 years of end stage renal disease and 4 months of pulmonary tuberculosis and managed by continuous ambulatory peritoneal dialysis and anti-tuberculosis medications. On the 5th hospital day, esophagogastroduodenoscopy was underwent
to
remove the pieces of thermometer accidentaly broken, which revealed the 1.0cm ulcerative lesion on the posterior wall of the upper body of stomach. The base of ulcer was coated with whitish-yellow dirty exudates and slightly irregular and the
margin was
nodular. The mucosae were friable and easily bled with light touch. The histologic examination of biopsy specimen revealed the multiple non-septated fungal hyphae branching right-angle. ( Kor J Gastrointest Endosc 16: 82~85, 1996)
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